Research from Barcelona on mice with genetic predisposition for Alzheimer's Disease showed that a combination of melatonin and exercise lowered their risk for developing the disease. This combination protected the brain from oxidative stress and from excesses of amyloid and tau proteins. It also improves energy production in the brain, which is what ultimately leads to memory issues and deterioration.
Melatonin is a very powerful hormone with anti-oxidant properties that is often used as a sleeping aid, for jet lag, and as a treatment for cancer. Its major function is to regulate hormone production of most hormone systems in the body. When it is used in milligram doses it is thousands of times the dosages secreted by the pineal gland.
